ASPH-IN-1
ASPH-IN-1 (Compound 14c) is an orally active ASPH inhibitor. ASPH-IN-1 down-regulates MMP2 and MMP14 protein expression. ASPH-IN-1 exhibits anti-cancer activity against cholangiocarcinoma[1].
Product Specifications
CAS Number
[2477878-52-5]
UNSPSC
12352005
Target
MMP
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(OC)C1=CC=C(C=C1)C2OC(N)=C(OS(=O)(=O)CC=3C=CC=CC3)C2=O
Molecular Formula
C19H17NO7S
Molecular Weight
403.41
References & Citations
[1]Jack R. Wands, et al. Targeting aspartate beta-hydroxylase suppresses tumor malignancy and metastasis. US20210052561A1. United States. 2020-08-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-14; MMP-2
Curated Selection
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