BI-7190

BI-7190 is a selective BPTF inhibitor (Kd = 3.5 nM) . BI-7190 can be used in the research of cancer[1][2].

Product Specifications

CAS Number

[2001082-11-5]

UNSPSC

12352005

Target

Epigenetic Reader Domain

Related Pathways

Epigenetics

Field of Research

Cancer

Smiles

O=C1C(=C(C(=CN1C)C=2C=CC(=C(OC)C2)C3(N4CCN(C)CC4)CC3)C)C

Molecular Formula

C23H31N3O2

Molecular Weight

381.52

References & Citations

[1]Buchholz C R. Chemical Probe Development for Bromodomain and PHD Finger-containing Transcription Factor (BPTF) Reader Domains as Anti-Cancer Therapy[D]. University of Minnesota, 2023. |[2]Martinelli P, et al. Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments. ChemMedChem. 2023 Mar 14;18 (6) :e202200686.