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Ricolinostat (Standard)

Ricolinostat (Standard) is the analytical standard of Ricolinostat. This product is intended for research and analytical applications. Ricolinostat (ACY-1215) is a potent and selective HDAC6 inhibitor, with an IC50 of 5 nM. ACY-1215 also inhibits HDAC1, HDAC2, and HDAC3 with IC50s of 58, 48, and 51 nM, respectively.

Product Specifications

CAS Number

1316214-52-4

UNSPSC

12352100

Target

Apoptosis; HDAC; Reference Standards

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Epigenetics; Others

Field of Research

Cancer

Smiles

O=C(C1=CN=C(N(C2=CC=CC=C2)C3=CC=CC=C3)N=C1)NCCCCCCC(NO)=O

Molecular Formula

C24H27N5O3

Molecular Weight

433.50

References & Citations

[1]Santo L, et al. Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with PS-341 in multiple myeloma. Blood. 2012 Mar 15;119 (11) :2579-89.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

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