Bacillibactin

Bacillibactin (Corynebactin) is a cyclic tricatecholate siderophore. Bacillibactin’s primary function is to facilitate bacterial iron acquisition by chelating iron ions (Fe3+) from the environment, thereby aiding bacterial survival under iron-limited conditions. Bacillibactin exhibits direct antimicrobial activity, such as inhibition of the growth of the producing bacteria Pseudomonas aeruginosa and Aeromonas veronae, as well as plant pathogens such as Pseudomonas syringae.Bacillibactin can be used in antibacterial and antifungal research[1][2][3][4].

Product Specifications

CAS Number

[95536-41-7]

Product Name Alternative

Corynebactin

UNSPSC

12352005

Target

Bacterial; Fungal

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(C1=C(C(O)=CC=C1)O)NCC(N[C@H]2[C@H](OC([C@H]([C@H](OC([C@H]([C@H](OC2=O)C)NC(CNC(C3=C(C(O)=CC=C3)O)=O)=O)=O)C)NC(CNC(C4=C(C(O)=CC=C4)O)=O)=O)=O)C)=O

Molecular Formula

C39H42N6O18

Molecular Weight

882.78

References & Citations

[1]Prazdnova E, et al. Bacillibactin, a Potential Bacillus-Based Antibacterial Non-Ribosomal Peptide: In Silico Studies for Targeting Common Fish Pathogens. Int J Mol Sci. 2025 Jun 17;26 (12) :5811. |[2]Pi H, Helmann JD. Genome-Wide Characterization of the Fur Regulatory Network Reveals a Link between Catechol Degradation and Bacillibactin Metabolism in Bacillus subtilis. mBio. 2018 Oct 30;9 (5) :e01451-18.|[3]Dimopoulou A, et al. Direct Antibiotic Activity of Bacillibactin Broadens the Biocontrol Range of Bacillus amyloliquefaciens MBI600. mSphere. 2021 Aug 25;6 (4) :e0037621.|[4]Zhou M, et al. Bacillibactin and Bacillomycin Analogues with Cytotoxicities against Human Cancer Cell Lines from Marine Bacillus sp. PKU-MA00093 and PKU-MA00092. Mar Drugs. 2018 Jan 10;16 (1) :22.