DC-159a
DC-159a is an 8-methoxyfluoroquinolone with broad-spectrum antimicrobial activity, especially against Gram-positive pathogens. DC-159a against Peptostreptococcus, Clostridium difficile, and Bacteroides fragilis with MIC90 values of 0.5, 4, and 2 μg/mL, respectively[1].
Product Specifications
CAS Number
[931411-93-7]
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
C[C@@]1(C2(CC2)CN(C(C(OC)=C3N([C@H]4[C@H](C4)F)C=C5C(O)=O)=C(F)C=C3C5=O)C1)N.O.[0.5]
Molecular Formula
C21H23F2N3O4.1/2H2O
Molecular Weight
428.43
References & Citations
[1]Hoshino K, et al. In vitro and in vivo antibacterial activities of DC-159a, a new fluoroquinolone. Antimicrob Agents Chemother. 2008 Jan;52 (1) :65-76.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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