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Antibiotic adjuvant 3

Antibiotic adjuvant 3 (compound 8g) is an antibiotic adjuvant with potent colistin-potentiating activity and low mammalian toxicity. Antibiotic adjuvant 3 has minimum re-sensitizing concentration of 0.25 μg/mL agnist of Escherichia coli AR-0493[1].

Product Specifications

CAS Number

2972593-21-6

UNSPSC

12352005

Target

Antibiotic

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

ClC1=CC=CC(NC2=NC3=NON=C3N=C2NCCCNC4=CC=C(Cl)C(C(F)(F)F)=N4)=C1

Molecular Formula

C19H15Cl2F3N8O

Molecular Weight

499.28

References & Citations

[1]Harris SL, et al. Extended structure-activity relationship studies of the [1,2,5]oxadiazolo[3,4-b]pyrazine-containing colistin adjuvants. Bioorg Med Chem Lett. 2025 Jan 1;115:130008.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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