Antibiotic adjuvant 3
Antibiotic adjuvant 3 (compound 8g) is an antibiotic adjuvant with potent colistin-potentiating activity and low mammalian toxicity. Antibiotic adjuvant 3 has minimum re-sensitizing concentration of 0.25 μg/mL agnist of Escherichia coli AR-0493[1].
Product Specifications
CAS Number
[2972593-21-6]
UNSPSC
12352005
Target
Antibiotic
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
ClC1=CC=CC(NC2=NC3=NON=C3N=C2NCCCNC4=CC=C(Cl)C(C(F)(F)F)=N4)=C1
Molecular Formula
C19H15Cl2F3N8O
Molecular Weight
499.28
References & Citations
[1]Harris SL, et al. Extended structure-activity relationship studies of the [1,2,5]oxadiazolo[3,4-b]pyrazine-containing colistin adjuvants. Bioorg Med Chem Lett. 2025 Jan 1;115:130008.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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