Antibiotic adjuvant 2
Antibiotic adjuvant 2 (compound 5q) is an antibiotic adjuvant with potent colistin-potentiating activity and low mammalian toxicity. Antibiotic adjuvant 2 has minimum re-sensitizing concentration of 0.125 μg/mL agnist of Escherichia coli AR-0493[1].
Product Specifications
UNSPSC
12352005
Target
Antibiotic
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
ClC(C=C1)=CC=C1CNC2=NC3=NON=C3N=C2NCC4=CC=C(Cl)C=C4
Molecular Formula
C18H14Cl2N6O
Molecular Weight
401.25
References & Citations
[1]Harris SL, et al. Extended structure-activity relationship studies of the [1,2,5]oxadiazolo[3,4-b]pyrazine-containing colistin adjuvants. Bioorg Med Chem Lett. 2025 Jan 1;115:130008.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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