P38α inhibitor 5
P38α inhibitor 5 (compound 1) is a PROTAC-type target protein ligand targeting p38 and can be used to synthesize NR-11c (HY-159798) [1].
Product Specifications
CAS Number
[2550397-96-9]
UNSPSC
12352005
Target
P38 MAPK
Related Pathways
MAPK/ERK Pathway
Field of Research
Cancer
Purity
98.69
Smiles
CC(C(N1C(C)=CC(OCC2=CC=C(C=C2F)F)=C(C1=O)Br)=C3)=CC=C3C(NCCCC#C)=O
Molecular Formula
C26H23BrF2N2O3
Molecular Weight
529.37
References & Citations
[1]Cubillos-Rojas M, et al. Synthesis and Biological Activity of a VHL-Based PROTAC Specific for p38α. Cancers (Basel) . 2023 Jan 18;15 (3) :611.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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