Cefetecol
Ceftezole (GR69153) is a broad-spectrum cephalosporin antibiotic and an α-glucosidase inhibitor. Ceftezole inhibits bacterial cell lysis by inhibiting cell wall synthesis and binding to penicillin-binding proteins (PBPs) . Ceftezole exhibits in vivo anti-diabetic activity in diabetic mice. Ceftezole can be used in antibacterial and anti-diabetic research[1][2].
Product Specifications
CAS Number
117211-03-7
Product Name Alternative
GR69153
UNSPSC
12352005
Target
Antibiotic; Bacterial; Glycosidase
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection; Metabolic Disease
Smiles
O=C1N2[C@@](SCC=C2C(O)=O)([H])[C@@H]1NC(/C(C3=CSC(N)=N3)=N\O[C@@H](C4=CC(O)=C(C=C4)O)C(O)=O)=O
Molecular Formula
C20H17N5O9S2
Molecular Weight
535.51
References & Citations
[1]Lee DS, et al. Ceftezole, a cephem antibiotic, is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity. Int J Mol Med. 2007 Sep;20 (3) :379-83.|[2]Noto T, et al. Ceftezole, a new cephalosporin C derivative I. In vitro and in vivo antimicrobial activity. J Antibiot (Tokyo) . 1976 Oct;29 (10) :1058-70.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Glucosidase; β-lactam
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