Cefetecol

Ceftezole (GR69153) is a broad-spectrum cephalosporin antibiotic and an α-glucosidase inhibitor. Ceftezole inhibits bacterial cell lysis by inhibiting cell wall synthesis and binding to penicillin-binding proteins (PBPs) . Ceftezole exhibits in vivo anti-diabetic activity in diabetic mice. Ceftezole can be used in antibacterial and anti-diabetic research[1][2].

Product Specifications

CAS Number

[117211-03-7]

Product Name Alternative

GR69153

UNSPSC

12352005

Target

Antibiotic; Bacterial; Glycosidase

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection; Metabolic Disease

Smiles

O=C1N2[C@@](SCC=C2C(O)=O)([H])[C@@H]1NC(/C(C3=CSC(N)=N3)=N\O[C@@H](C4=CC(O)=C(C=C4)O)C(O)=O)=O

Molecular Formula

C20H17N5O9S2

Molecular Weight

535.51

References & Citations

[1]Lee DS, et al. Ceftezole, a cephem antibiotic, is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity. Int J Mol Med. 2007 Sep;20 (3) :379-83.|[2]Noto T, et al. Ceftezole, a new cephalosporin C derivative I. In vitro and in vivo antimicrobial activity. J Antibiot (Tokyo) . 1976 Oct;29 (10) :1058-70.