Azido-methyltetrazine di-arm linker
Azido-methyltetrazine di-arm linker is a multivalent ADC linker for the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[2861998-16-3]
UNSPSC
12352203
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.75
Solubility
DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
[N-]=[N+]=NCCCNC([C@H](CCCCN)NC(CC1=CC=C(C2=NN=C(C)N=N2)C=C1)=O)=O
Molecular Formula
C20H28N10O2
Molecular Weight
440.50
References & Citations
[1]Yamazaki C M, et al. Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance[J]. Nature communications, 2021, 12 (1) : 3528.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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