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(R, R) -BMS-986397

(R, R) -BMS-986397 is a CK1α degrader (DC50 between 0.1-0.5 pM) . (R, R) -BMS-986397 can be used in anti-leukemia research[1].

Product Specifications

CAS Number

2564486-48-0

UNSPSC

12352005

Target

Casein Kinase

Related Pathways

Cell Cycle/DNA Damage; Stem Cell/Wnt

Field of Research

Cancer

Purity

99.70

Smiles

O=C1CC[C@@H](N2CC3=C(C=CC(C(N[C@H](C4=NC=CC=C4Cl)C(F)(F)F)=O)=C3)C2=O)C(N1)=O

Molecular Formula

C21H16ClF3N4O4

Molecular Weight

480.82

References & Citations

[1]Frans BACULI, et al. Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith. WO2020243379A1. Celgene Corporation. 2020-05-29.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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