(R, R) -BMS-986397
(R, R) -BMS-986397 is a CK1α degrader (DC50 between 0.1-0.5 pM) . (R, R) -BMS-986397 can be used in anti-leukemia research[1].
Product Specifications
CAS Number
[2564486-48-0]
UNSPSC
12352005
Target
Casein Kinase
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Field of Research
Cancer
Purity
99.70
Smiles
O=C1CC[C@@H](N2CC3=C(C=CC(C(N[C@H](C4=NC=CC=C4Cl)C(F)(F)F)=O)=C3)C2=O)C(N1)=O
Molecular Formula
C21H16ClF3N4O4
Molecular Weight
480.82
References & Citations
[1]Frans BACULI, et al. Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith. WO2020243379A1. Celgene Corporation. 2020-05-29.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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