Thalidomide 5-azetidine-2C-oxotetrahydropyrimidin-bromophenyl
Thalidomide 5-azetidine-2C-oxotetrahydropyrimidin-bromophenyl is an E3 Ligase Ligand-Linker Conjugate. Thalidomide 5-azetidine-2C-oxotetrahydropyrimidin-bromophenyl can be used to synthesize PROTAC GSPT1 degrader-1 (HY-159609) [1].
Product Specifications
CAS Number
[3034310-00-1]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1NC(C(CC1)N2C(C3=CC=C(N4CC(CCN5C(N(CCC5)C6=CC(Br)=CC=C6)=O)C4)C=C3C2=O)=O)=O
Molecular Formula
C28H28BrN5O5
Molecular Weight
594.46
References & Citations
[1]Tetrahydropyrimidine derivatives as GSPT1 degraders and their preparation. World Intellectual Property Organization, WO2024073871 A1. 2024-04-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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