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Thalidomide 5-azetidine-2C-oxotetrahydropyrimidin-bromophenyl

Thalidomide 5-azetidine-2C-oxotetrahydropyrimidin-bromophenyl is an E3 Ligase Ligand-Linker Conjugate. Thalidomide 5-azetidine-2C-oxotetrahydropyrimidin-bromophenyl can be used to synthesize PROTAC GSPT1 degrader-1 (HY-159609) [1].

Product Specifications

CAS Number

[3034310-00-1]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C1NC(C(CC1)N2C(C3=CC=C(N4CC(CCN5C(N(CCC5)C6=CC(Br)=CC=C6)=O)C4)C=C3C2=O)=O)=O

Molecular Formula

C28H28BrN5O5

Molecular Weight

594.46

References & Citations

[1]Tetrahydropyrimidine derivatives as GSPT1 degraders and their preparation. World Intellectual Property Organization, WO2024073871 A1. 2024-04-11.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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