AZD1981 (Standard)
AZD1981 (Standard) is the analytical standard of AZD1981. This product is intended for research and analytical applications. AZD1981 is the antagonist for GPR44 (also known also PTGDR2, DP2 or CRTh) . AZD1981 blocks the binding of PGD2 to CRTH2. AZD1981 exhibits immunomodulatory effects and can be used in research of chronic spontaneous urticaria[1][2].
Product Specifications
CAS Number
802904-66-1
UNSPSC
12352100
Target
CRTH2 (GPR44) ; Prostaglandin Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology
Smiles
O=C(O)CN1C(C)=C(SC2=CC=C(Cl)C=C2)C3=C1C=CC=C3NC(C)=O
Molecular Formula
C19H17ClN2O3S
Molecular Weight
388.87
References & Citations
[1]Hu S, et al., PGD2 displays distinct effects in diffuse large B-cell lymphoma depending on different concentrations. Cell Death Discov. 2023 Feb 1;9 (1) :39.|[2]Oliver ET, et al., Effects of an Oral CRTh2 Antagonist (AZD1981) on Eosinophil Activity and Symptoms in Chronic Spontaneous Urticaria. Int Arch Allergy Immunol. 2019;179 (1) :21-30.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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