DMOG (Standard)
DMOG (Standard) is the analytical standard of DMOG. This product is intended for research and analytical applications. DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo[1]. DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal[2][4]. DMOG induces cell autophagy[5].
Product Specifications
UNSPSC
12352100
Hazard Statement
H302
Target
Autophagy; HIF/HIF Prolyl-Hydroxylase; Reference Standards
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Purity
98.52
Smiles
O=C(OC)CNC(C(OC)=O)=O
Molecular Formula
C6H9NO5
Molecular Weight
175.14
Precautions
H302
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15893R/DMOG-Standard-SDS-MedChemExpress.pdf
Scientific Category
Reference Standards
Clinical Information
No Development Reported
CAS Number
[89464-63-1]
Available Sizes
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