MTDB-Alkyne
MTDB-Alkyne is an alkyne-containing click chemistry reagent. MTDB-Alkyne can be used to synthesize Proximity-Induced Nucleic Acid Degrader (PINAD) for the degradation of SARS-CoV-2 RNA[1].
Product Specifications
CAS Number
[2923694-73-7]
Product Name Alternative
MTDB-Alk
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(C1=C(NC(N2CCN(CCC2)CC3=CSC(C)=N3)=O)C=CC=C1)NCC#C
Molecular Formula
C21H25N5O2S
Molecular Weight
411.52
References & Citations
[1]Mikutis S, et al. Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules. ACS Cent Sci. 2023 Apr 26;9 (5) :892-904.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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