Enpp-1-IN-21

Enpp-1-IN-21 (compound 4g) is an inhibitor of ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), with IC50 values for ENPP1 and ENPP3 at 0.45 and 0.19 μM, respectively[1].

Product Specifications

CAS Number

[2803505-78-2]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Purity

99.07

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C)C=C1)NC2=CC=C(C=C2)OS(=O)(C3=CC=C(C=C3)OC(F)(F)F)=O

Molecular Formula

C21H16F3NO5S

Molecular Weight

451.42

References & Citations

[1]Saif Ullah, et al. Synthesis and Biological Evaluation of Arylamide Sulphonate Derivatives as Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 and -3 Inhibitors. ACS Omega. 2022 Jul 19;7 (30) :26905-26918.