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Ferroptocide

Ferroptocide is a cell death inducer that triggers ferroptosis and has anti-tumor activity. Ferroptocide can induce oxidative stress, leading to G2/M cell cycle arrest and apoptosis activation in LNCaP cells, while also effectively inhibiting the cell viability of both LNCaP and TRAMP-C1 cells. Ferroptocide can be used to study its capability to induce mitochondrial autophagy and to trigger immunogenic cell death (ICD) in prostate cancer cells[1].

Product Specifications

CAS Number

2505218-38-0

UNSPSC

12352005

Target

Apoptosis; Autophagy; Ferroptosis

Related Pathways

Apoptosis; Autophagy

Field of Research

Cancer

Smiles

O[C@@]12[C@@]3(C[C@@H](C2=O)O)[C@H]([C@H](C4=CCN(C(N(C5=CC=CC=C5)C6=O)=O)N6C4)C[C@H]([C@@]1([C@@H](CC3)C)C)OC(CCl)=O)C

Molecular Formula

C30H36ClN3O7

Molecular Weight

586.08

References & Citations

[1]Hillary Shah, et al. Evaluation of Ferroptocide (FTC) As a Potential Immunogenic Cell Death Inducing Agent in Prostate Cancer Cells. Biochemistry and Molecular Biology. 2021.35.S1.03356.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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