Ferroptocide

Ferroptocide is a cell death inducer that triggers ferroptosis and has anti-tumor activity. Ferroptocide can induce oxidative stress, leading to G2/M cell cycle arrest and apoptosis activation in LNCaP cells, while also effectively inhibiting the cell viability of both LNCaP and TRAMP-C1 cells. Ferroptocide can be used to study its capability to induce mitochondrial autophagy and to trigger immunogenic cell death (ICD) in prostate cancer cells[1].

Product Specifications

CAS Number

[2505218-38-0]

UNSPSC

12352005

Target

Apoptosis; Autophagy; Ferroptosis

Related Pathways

Apoptosis; Autophagy

Field of Research

Cancer

Smiles

O[C@@]12[C@@]3(C[C@@H](C2=O)O)[C@H]([C@H](C4=CCN(C(N(C5=CC=CC=C5)C6=O)=O)N6C4)C[C@H]([C@@]1([C@@H](CC3)C)C)OC(CCl)=O)C

Molecular Formula

C30H36ClN3O7

Molecular Weight

586.08

References & Citations

[1]Hillary Shah, et al. Evaluation of Ferroptocide (FTC) As a Potential Immunogenic Cell Death Inducing Agent in Prostate Cancer Cells. Biochemistry and Molecular Biology. 2021.35.S1.03356.