(6E) -SR 11302
(6E) -SR 11302 is a E-isomer of SR 11302. SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE) [1].
Product Specifications
CAS Number
1386982-70-2
UNSPSC
12352211
Target
AP-1
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Purity
99.68
Smiles
CC1(C)C(/C=C/C(C2=CC=C(C=C2)C)=C\C=C\C(C)=C\C(O)=O)=C(C)CCC1
Molecular Formula
C26H32O2
Molecular Weight
376.53
References & Citations
[1]C Huang, et al. Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid. Proc Natl Acad Sci U S A. 1997 May 27;94 (11) :5826-30.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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