(4R,5S) -YX-02-030
(4R,5S) -YX-02-030 is an isomer of YX-02-030 (HY-158684) . YX-02-030 is a PROTAC MDM2 degrader[1].
Product Specifications
CAS Number
[3049077-01-9]
UNSPSC
12352005
Target
Drug Isomer
Related Pathways
Others
Field of Research
Cancer
Purity
99.63
Smiles
O=C(CN1CCN(C(N2[C@@](C)(C3=CC=C(Cl)C=C3)[C@@](C)(C4=CC=C(Cl)C=C4)N=C2C5=CC=C(C(C)(C)C)C=C5OCC)=O)CC1)NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N6[C@H](C(NCC7=CC=C(C8=C(C)N=CS8)C=C7)=O)C[C@@H](O)C6)=O)=O
Molecular Formula
C66H85Cl2N9O10S
Molecular Weight
1267.41
References & Citations
[1]Adams CM, et al. Targeted MDM2 Degradation Reveals a New Vulnerability for p53-Inactivated Triple-Negative Breast Cancer. Cancer Discov. 2023 May 4;13 (5) :1210-1229.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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