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(4R,5S) -YX-02-030

(4R,5S) -YX-02-030 is an isomer of YX-02-030 (HY-158684) . YX-02-030 is a PROTAC MDM2 degrader[1].

Product Specifications

CAS Number

[3049077-01-9]

UNSPSC

12352005

Target

Drug Isomer

Related Pathways

Others

Field of Research

Cancer

Purity

99.63

Smiles

O=C(CN1CCN(C(N2[C@@](C)(C3=CC=C(Cl)C=C3)[C@@](C)(C4=CC=C(Cl)C=C4)N=C2C5=CC=C(C(C)(C)C)C=C5OCC)=O)CC1)NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N6[C@H](C(NCC7=CC=C(C8=C(C)N=CS8)C=C7)=O)C[C@@H](O)C6)=O)=O

Molecular Formula

C66H85Cl2N9O10S

Molecular Weight

1267.41

References & Citations

[1]Adams CM, et al. Targeted MDM2 Degradation Reveals a New Vulnerability for p53-Inactivated Triple-Negative Breast Cancer. Cancer Discov. 2023 May 4;13 (5) :1210-1229.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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