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Revefenacin-d4

Revefenacin-d4 (TD-4208-d4) is deuterium labeled Revefenacin. Revefenacin (TD-4208; GSK1160724) is a potent mAChR antagonist; has a high affinity on M3 receptor with a Ki of 0.18 nM.

Product Specifications

Product Name Alternative

TD-4208-d4; GSK1160724-d4

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Smiles

O=C(NC1=CC=CC=C1C2=CC=CC=C2)OC3CCN(CC3)CCN(C)C(C4=C(C([2H])=C(C([2H])=C4[2H])CN5CCC(CC5)C(N)=O)[2H])=O

Molecular Formula

C35H39D4N5O4

Molecular Weight

601.77

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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