E-5531
E-5531 is an endotoxin antagonist. E-5531 quickly becomes inactive after binding with HDL. E-5531 can block the Toll like receptor 4 (TLR4) signaling pathway. E-5531 can be used for the study of endotoxemia and septic shock[1].
Product Specifications
CAS Number
162679-36-9
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
CCCCCC/C=C\CCCC(O[C@H](CCCCCCC)CCO[C@@H]1[C@H]([C@@H](O[C@@H]([C@H]1OP(O)(O)=O)COC)OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)OP(O)(O)=O)NC(CC(CCCCCCCCCCC)=O)=O)OCC[C@H](O)CCCCCCC)O)NC(CC(CCCCCCCCCCC)=O)=O)=O
Molecular Formula
C73H136N2O22P2
Molecular Weight
1455.81
References & Citations
[1]Ondiveeran H K, et al. E-5564 Eisai[J]. IDrugs, 2004, 7 (6) : 582-590.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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