(R, R) -ART0380
(R, R) -ART0380 (Compound 38) is the enantiomer of ART0380. ART0380 is a potent and selective ATR inhibitor. ART0380 can be used in studies of advanced or metastatic solid tumors[1].
Product Specifications
CAS Number
2267316-75-4
UNSPSC
12352005
Target
Drug Isomer
Related Pathways
Others
Field of Research
Cancer
Purity
99.06
Smiles
C[C@@H]1COCCN1C2=NC(C3=CC=NC(N)=C3)=NC(N=[S@@](C)(C4CC4)=O)=C2
Molecular Formula
C18H24N6O2S
Molecular Weight
388.49
References & Citations
[1]Carroll CL, et al. Discovery of ART0380, a Potent and Selective ATR Kinase Inhibitor Undergoing Phase 2 Clinical Studies for the Treatment of Advanced or Metastatic Solid Cancers. J Med Chem. 2024 Dec 26;67 (24) :21890-21904.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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