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(R, R) -ART0380

(R, R) -ART0380 (Compound 38) is the enantiomer of ART0380. ART0380 is a potent and selective ATR inhibitor. ART0380 can be used in studies of advanced or metastatic solid tumors[1].

Product Specifications

CAS Number

2267316-75-4

UNSPSC

12352005

Target

Drug Isomer

Related Pathways

Others

Field of Research

Cancer

Purity

99.06

Smiles

C[C@@H]1COCCN1C2=NC(C3=CC=NC(N)=C3)=NC(N=[S@@](C)(C4CC4)=O)=C2

Molecular Formula

C18H24N6O2S

Molecular Weight

388.49

References & Citations

[1]Carroll CL, et al. Discovery of ART0380, a Potent and Selective ATR Kinase Inhibitor Undergoing Phase 2 Clinical Studies for the Treatment of Advanced or Metastatic Solid Cancers. J Med Chem. 2024 Dec 26;67 (24) :21890-21904.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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