Elobixibat-d5
Elobixibat-d5 is the deuterium labeled Elobixibat. Elobixibat (A 3309; AZD 7806) is orally active, bile acid transporter (IBAT) inhibitor with IC50 values ??of 0.53 nM (human IBAT), 0.13 nM (mouse IBAT), and 5.8 nM (canine IBAT). Elobixibat can lower LDL cholesterol, increase serum GLP-1, promote colonic motility, and has the potential to treat metabolic syndrome. Elobixibat can be used in the study of chronic functional constipation (CIC), dyslipidemia, non-alcoholic hepatitis, and liver tumors in the elderly[1][2][3][4].
Product Specifications
Product Name Alternative
A 3309-d5; AZD 7806-d5
UNSPSC
12352005
Target
Apical Sodium-Dependent Bile Acid Transporter; Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Cancer
Smiles
O=C(COC(C=C1C(N(CC(CCCC)(CCCC)CS1(=O)=O)C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=C3)=C3SC)N[C@@H](C(NCC(O)=O)=O)C4=CC=CC=C4
Molecular Formula
C36H40D5N3O7S2
Molecular Weight
700.92
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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