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Ribociclib (hydrochloride) (Standard)

Ribociclib (Standard) (LEE011 (Standard) ) hydrochloride is the analytical standard of Ribociclib hydrochloride (HY-15777A) . This product is intended for research and analytical applications. Ribociclib hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.

Product Specifications

CAS Number

[1211443-80-9]

Product Name Alternative

LEE011 (hydrochloride) (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

CDK; Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Others

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Purity

99.96

Smiles

O=C(N(C)C)C1=CC2=C(N1C3CCCC3)N=C(NC4=NC=C(N5CCNCC5)C=C4)N=C2.Cl

Molecular Formula

C23H31ClN8O

Molecular Weight

471.00

Precautions

H302, H315, H319, H335

Shipping Conditions

Blue Ice

Storage Conditions

4°C, sealed and dry storage, away from light and moisture

Scientific Category

Reference Standards

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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