Ribociclib (hydrochloride) (Standard)
Ribociclib (Standard) (LEE011 (Standard) ) hydrochloride is the analytical standard of Ribociclib hydrochloride (HY-15777A) . This product is intended for research and analytical applications. Ribociclib hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.
Product Specifications
CAS Number
[1211443-80-9]
Product Name Alternative
LEE011 (hydrochloride) (Standard)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CDK; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Others
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
99.96
Smiles
O=C(N(C)C)C1=CC2=C(N1C3CCCC3)N=C(NC4=NC=C(N5CCNCC5)C=C4)N=C2.Cl
Molecular Formula
C23H31ClN8O
Molecular Weight
471.00
Precautions
H302, H315, H319, H335
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed and dry storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Available Sizes
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