Rociletinib (Standard)
Rociletinib (Standard) is the analytical standard of Rociletinib. This product is intended for research and analytical applications. Rociletinib (CO-1686) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively.
Product Specifications
CAS Number
1374640-70-6
UNSPSC
12352100
Target
EGFR; Reference Standards
Related Pathways
JAK/STAT Signaling; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
C=CC(NC1=CC=CC(NC2=NC(NC3=CC=C(N4CCN(C(C)=O)CC4)C=C3OC)=NC=C2C(F)(F)F)=C1)=O
Molecular Formula
C27H28F3N7O3
Molecular Weight
555.55
References & Citations
[1]Walter AO, et al. Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC. Cancer Discov. 2013 Sep 25.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LY421869 100 µg
Sex Hormone Binding GlobuLin (SHBG) (NM_001040) Human Over-expression Lysate
Sign In for Pricing
View Details 
TP303497M 100 µg
Transketolase (TKT) (NM_001064) Human Recombinant Protein
Sign In for Pricing
View Details