NSC 23766 (Standard)
NSC 23766 (Standard) is the analytical standard of NSC 23766. This product is intended for research and analytical applications. NSC 23766 is a cell-permeable, reversible and specific inhibitor of Rac GTPase, used for cancer treatment.
Product Specifications
CAS Number
733767-34-5
UNSPSC
12352100
Target
Ras; Reference Standards
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; Others
Field of Research
Cancer
Smiles
NC1=CC(C)=NC2=CC=C(NC3=NC(NC(C)CCCN(CC)CC)=NC(C)=C3)C=C12
Molecular Formula
C24H35N7
Molecular Weight
421.58
References & Citations
[1]Veluthakal R, et al. NSC23766, a Known Inhibitor of Tiam1-Rac1 Signaling Module, Prevents the Onset of Type 1 Diabetes in the NOD Mouse Model. Cell Physiol Biochem. 2016;39 (2) :760-7.|[2]Song SJ, et al. Inhibition of Rac1 GTPase activity affects porcine oocyte maturation and early embryo development. Sci Rep. 2016 Oct 3;6:34415|[3]Zhao L, et al. Rac1 modulates the formation of primordial follicles by facilitating STAT3-directed Jagged1, GDF9 and BMP15 transcription in mice. Sci Rep. 2016 Apr 6;6:23972|[4]Wang Y, et al. Involvement of Rac1 signalling pathway in the development and maintenance of acute inflammatory pain induced by bee venom injection. Br J Pharmacol. 2016 Mar;173 (5) :937-50
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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