Zibrofusidic acid
Zibrofusidic acid (24-Bromofusidic acid; TD-1414) is a brominated derivative of Fusidic acid. Zibrofusidic acid can be combined within the hydrophobic groove formed by the transmembrane helix 1 (TM1) and the transmembrane helix 2 (TM2) of the AcrB protein. Zibrofusidic acid can be used for the research of multidrug efflux pump[1].
Product Specifications
CAS Number
827603-95-2
Product Name Alternative
24-Bromofusidic acid; TD-1414
UNSPSC
12352211
Target
Drug Derivative
Related Pathways
Others
Field of Research
Others
Smiles
C[C@@]([C@](C[C@H]1O)([H])/C2=C(C(O)=O)\CC/C(Br)=C(C)/C)(C[C@@H]2OC(C)=O)[C@]([C@]1([H])[C@]3(CC[C@H]4O)C)(CC[C@@]3([H])[C@@H]4C)C
Molecular Formula
C31H47BrO6
Molecular Weight
595.61
References & Citations
[1]Oswald C, et al. Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB. Nat Commun. 2016 Dec 16;7:13819.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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