IDO5L (Standard)

IDO5L (Standard) is the analytical standard of IDO5L. This product is intended for research and analytical applications. IDO5L is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 67 nM.

Product Specifications

CAS Number

[914471-09-3]

UNSPSC

12352100

Target

Indoleamine 2,3-Dioxygenase (IDO) ; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

ON/C(C1=NON=C1N)=N/C2=CC=C(F)C(Cl)=C2

Molecular Formula

C9H7ClFN5O2

Molecular Weight

271.64

References & Citations

[1]Yue EW, et al. Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model. J Med Chem. 2009 Dec 10;52 (23) :7364-7.|[2]Huang X, et al. Synthesis of [ (18) F] 4-amino-N- (3-chloro-4-fluorophenyl) -N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide (IDO5L) : a novel potential PET probe for imaging of IDO1 expression. J Labelled Comp Radiopharm. 2015 Apr;58 (4) :156-62.