TTNPB (Standard)

TTNPB (Standard) is the analytical standard of TTNPB. This product is intended for research and analytical applications. TTNPB is a highly potent RAR agonist. Competitive binding assays using human RARs yield IC50s of α=5.1 nM, β= 4.5 nM, and γ=9.3 nM, respectively.

Product Specifications

CAS Number

[71441-28-6]

Product Name Alternative

Ro 13-7410 (Standard) ; Arotinoid acid (Standard) ; AGN191183 (Standard)

UNSPSC

12352005

Target

Apoptosis; Autophagy; RAR/RXR; Reference Standards

Related Pathways

Apoptosis; Autophagy; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

O=C(O)C1=CC=C(/C=C(C2=CC=C3C(C)(C)CCC(C)(C)C3=C2)\C)C=C1

Molecular Formula

C24H28O2

Molecular Weight

348.48

References & Citations

[1]Pignatello MA, et al. Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410) : binding affinities and disposition. Toxicol Appl Pharmacol. 1997 Feb;142 (2) :319-27.