SM-360320 drug-linker

SM-360320 drug-linker (compound 19), a drug-linker of SM-360320 (HY-125390), is a small molecule immune agonist. SM-360320 drug-linker can be used to conjugated to PD-1 antibodies to form antibodies in resisting tumors[1].

Product Specifications

CAS Number

[2064235-35-2]

UNSPSC

12352005

Target

Toll-like Receptor (TLR)

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(CCOCCOCCNC(CCC(NCC1=CC=C(CN2C(NC3=C2N=C(OCCOC)N=C3N)=O)C=C1)=O)=O)O

Molecular Formula

C27H37N7O9

Molecular Weight

603.62

References & Citations

[1]Guangyi Jin, et al. A novel antibody combining small molecule immune agonist and PD-1 antibody and its application in anti-tumor. CN106267188. 2017-01-04.