Estradiol 3,4-quinone

Estradiol 3,4-quinone (E2-3,4-Q) is a metabolite of Estradiol (HY-B0141) . Estradiol 3,4-quinone is a highly electrophilic compound and can induce cancer initiating mutations[1].

Product Specifications

CAS Number

[144082-88-2]

UNSPSC

12352211

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=C(C(C(C=C4)=O)=O)CC3

Molecular Formula

C18H22O3

Molecular Weight

286.37

References & Citations

[1]Cavalieri E, et al. The 3,4-Quinones of Estrone and Estradiol Are the Initiators of Cancer whereas Resveratrol and N-acetylcysteine Are the Preventers. Int J Mol Sci. 2021 Jul 30;22 (15) :8238.