MC-PEG2-VA-PAB-Exatecan
MC-PEG2-VA-PAB-Exatecan (Compound DL-18) is a Drug-Linker Conjugates for ADC. MC-PEG2-VA-PAB-Exatecan consists of Exatecan and a linker. MC-PEG2-VA-PAB-Exatecan can be used for synthesis of ADCs[1].
Product Specifications
CAS Number
2845165-13-9
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.61
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(OCC(C=C1)=CC=C1NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCN(C2=O)C(C=C2)=O)=O)=O)=O)N[C@@H]3C(C4=C5CC3)=C(CN6C7=CC([C@@]8(O)CC)=C(COC8=O)C6=O)C7=NC4=CC(F)=C5C
Molecular Formula
C51H56FN7O13
Molecular Weight
994.03
References & Citations
[1]Warren VIRICEL, et al. Enzyme-triggered self-reacting linker having improved physicochemical and pharmacological properties. Patent. WO2022207699.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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