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MC-PEG2-VA-PAB-Exatecan

MC-PEG2-VA-PAB-Exatecan (Compound DL-18) is a Drug-Linker Conjugates for ADC. MC-PEG2-VA-PAB-Exatecan consists of Exatecan (HY-13631) and a linker. MC-PEG2-VA-PAB-Exatecan can be used for synthesis of ADCs[1].

Product Specifications

CAS Number

[2845165-13-9]

UNSPSC

12352005

Target

Drug-Linker Conjugates for ADC; Topoisomerase

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

99.61

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(OCC(C=C1)=CC=C1NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCN(C2=O)C(C=C2)=O)=O)=O)=O)N[C@@H]3C(C4=C5CC3)=C(CN6C7=CC([C@@]8(O)CC)=C(COC8=O)C6=O)C7=NC4=CC(F)=C5C

Molecular Formula

C51H56FN7O13

Molecular Weight

994.03

References & Citations

[1]Warren VIRICEL, et al. Enzyme-triggered self-reacting linker having improved physicochemical and pharmacological properties. Patent. WO2022207699.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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