Votoplam (hydrochloride)

Votoplam (PTC518) hydrochloride is an HTT gene regulator with an IC50 ≤ 0.1 μM. Votoplam hydrochloride can be used in the research of Huntington's disease[1].

Product Specifications

CAS Number

[2407851-28-7]

Product Name Alternative

PTC518 (hydrochloride)

UNSPSC

12352100

Target

Huntingtin

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

OC1=C(C2=NN=C3C(N=NN3C4CC(C)(C)NC(C)(C4)C)=C2)C=CC(N5N=CC=N5)=C1.Cl

Molecular Formula

C21H26ClN9O

Molecular Weight

455.94

References & Citations

[1]Sydorenko, et al. Preparation of heterocyclic and heteroaryl compounds for treating Huntington's disease. World Intellectual Property Organization, WO2020005873 A1. 2020-01-02.