IPA-3 (Standard)
IPA-3 (Standard) is the analytical standard of IPA-3. This product is intended for research and analytical applications. IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, and shows no inhibition to group II PAKs (PAKs 4-6) .
Product Specifications
CAS Number
42521-82-4
UNSPSC
12352100
Target
PAK; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Others
Field of Research
Cancer
Smiles
OC1=CC=C2C=CC=CC2=C1SSC3=C4C=CC=CC4=CC=C3O
Molecular Formula
C20H14O2S2
Molecular Weight
350.45
References & Citations
[1]Viaud J, et al. An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently. Mol Cancer Ther. 2009 Sep;8 (9) :2559-65.|[2]Flaiz C, et al. PAK kinase regulates Rac GTPase and is a potential target in human schwannomas. Exp Neurol. 2009 Jul;218 (1) :137-44.|[3]Deacon SW, et al. An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase. Chem Biol. 2008 Apr;15 (4) :322-31
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MR211131L4V 200 µL
Hip1 (NM_146001) Mouse Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 
38221116 3x 1.0 µg
Pvrl3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
Sign In for Pricing
View Details 
LV736173 1.0 µg DNA
NF1P2 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)
Sign In for Pricing
View Details 