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IPA-3 (Standard)

IPA-3 (Standard) is the analytical standard of IPA-3. This product is intended for research and analytical applications. IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, and shows no inhibition to group II PAKs (PAKs 4-6) .

Product Specifications

CAS Number

42521-82-4

UNSPSC

12352100

Target

PAK; Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Others

Field of Research

Cancer

Smiles

OC1=CC=C2C=CC=CC2=C1SSC3=C4C=CC=CC4=CC=C3O

Molecular Formula

C20H14O2S2

Molecular Weight

350.45

References & Citations

[1]Viaud J, et al. An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently. Mol Cancer Ther. 2009 Sep;8 (9) :2559-65.|[2]Flaiz C, et al. PAK kinase regulates Rac GTPase and is a potential target in human schwannomas. Exp Neurol. 2009 Jul;218 (1) :137-44.|[3]Deacon SW, et al. An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase. Chem Biol. 2008 Apr;15 (4) :322-31

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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