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Thiophosphoro alkyne dichloridate

Thiophosphoro alkyne dichloridate (TPAC) is a thio-phosphonyl dichloride reagent based on the biomimetic design of histidine phosphorylation. Thiophosphoro alkyne dichloridate can selectively covalently couple with histidine and can be used for the development of protein function probes[1].

Product Specifications

CAS Number

21300-59-4

Product Name Alternative

TPAC

UNSPSC

12352100

Target

Others

Related Pathways

Others

Field of Research

Others

Smiles

S=P(Cl)(Cl)OCC#C

Molecular Formula

C3H3Cl2OPS

Molecular Weight

189.00

References & Citations

[1]Jia S, et al. Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation. J Am Chem Soc. 2019 May 8;141 (18) :7294-7301.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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