MRS4654
MRS4654 is an efficient and neutral P2Y14R (hP2Y14R IC50 = 15.0 nM, mP2Y14R IC50 = 18.6 nM) antagonist. MRS4654 has analgesic and anti-inflammatory effects. MRS4654 can be used for research on asthma and neuropathic pain[1].
Product Specifications
CAS Number
2765570-58-7
UNSPSC
12352005
Target
P2Y Receptor
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=C(C1=CC2=CC(C3=CC=C(C(F)(F)F)C=C3)=CC=C2C(C4=CC=C(C5=NOC(CO)=C5)C=C4)=C1)O
Molecular Formula
C28H18F3NO4
Molecular Weight
489.44
References & Citations
[1]Jung YH, et al. Structure-Activity Relationship of Heterocyclic P2Y14 Receptor Antagonists: Removal of the Zwitterionic Character with Piperidine Bioisosteres. J Med Chem. 2021 Apr 22;64 (8) :5099-5122.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2Y14 Receptor
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