C2 Adamantanyl galactosylceramide (d18:1/2:0)
C2 Adamantanyl galactosylceramide (AdaGalCer) (d18:1/2:0) is a bioactive sphingolipid. C2 Adamantanyl galactosylceramide (d18:1/2:0) stimulates glucocerebrosidase activity in vitro. C2 Adamantanyl galactosylceramide (d18:1/2:0) inhibits microsomal LacCer and Gb3 synthase, and inhibits cell sulfatide synthesis. C2 Adamantanyl galactosylceramide (d18:1/2:0) reduces glucosylceramide (GlcCer) levels in normal and lysosomal storage disease (LSD) cells. C2 Adamantanyl galactosylceramide (d18:1/2:0) acts as a substrate for A4GALT and is able to lower Gb3 levels with an IC50 concentration of 40 μM in fabry disease cells[1][2].
Product Specifications
CAS Number
574738-16-2
Product Name Alternative
AdaGalCer (d18:1/2:0) ; Admantanyl galactosylceramide (d18:1/2:0) ; Admantanyl galCer (d18:1/2:0)
UNSPSC
12352005
Target
Glucosylceramide Synthase (GCS) ; Glycosidase; Glycosyltransferase
Related Pathways
Epigenetics; Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Metabolic Disease
Smiles
OC[C@H]([C@@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CC23CC4CC(CC(C4)C3)C2)=O
Molecular Formula
C36H63NO8
Molecular Weight
637.89
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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