CGS 24565
CGS 24565, a derivative of the antibiotic Rifamycin (HY-B1907A), is an orally active hypolipidemic agent. CGS 24565 can reduce plasma cholesterol levels in both primate and nonprimate species[1][2].
Product Specifications
CAS Number
[136583-72-7]
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Field of Research
Cardiovascular Disease
Smiles
C[C@H]([C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)/C=C/O[C@](O1)(C)[C@H](O)C2=C1C(C)=C(OC(C(C)(C)C)=O)C3=C4C(N=C5O4)=C(N6CCN(CC7=C(C=C(C=C7C)C)C)CC6)C(OC)=C32)/C=C/C=C5/C
Molecular Formula
C57H77N3O12
Molecular Weight
996.23
References & Citations
[1]Gibson JC, et al. The ansamycins: hypolipidemic agents stimulating cholesterol removal by nonclassical mechanisms. J Lipid Res. 1994 Sep;35 (9) :1524-34.|[2]Schiavo DM, et al. Ocular changes in beagle dogs following oral administration of CGS 24565, a potential hypolipidemic agent. Toxicol Sci. 2000 May;55 (1) :189-94.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156192/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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