Cholic acid anilide

Cholic acid anilide, a Narylcholan-24-amide, is a potent inhibitor of C. difficile spore germination with an IC50 value of 1.8 μM in the spore germination assay conducted in Sodium phosphate media containing 6 mM Taurocholate (HY-B1131) and 12 mM Glycine (HY-Y0966) . Cholic acid anilide has the potential for C. difficile infections research[1].

Product Specifications

CAS Number

[6912-96-5]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Purity

99.9

Solubility

DMSO : 10 mg/mL (ultrasonic; warming)

Smiles

O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(NC4=CC=CC=C4)=O)([C@H](C[C@]2([H])[C@@]5([C@](C[C@@H](CC5)O)([H])C1)C)O)C

Molecular Formula

C30H45NO4

Molecular Weight

483.68

References & Citations

[1]Yufei Ma, et al. Exploration of plant-derived natural polyphenols toward COVID-19 main protease inhibitors: DFT, molecular docking approach, and molecular dynamics simulations. RSC Adv. 2022 Feb 14;12 (9) :5357-5368.