MZE-001

MZE-001 (compound 783) is a glycogen synthase 1 (GYS1) inhibitor. MZE-001 can be used for the study of GYS1 -mediated disease, such as Gaucher and Fabry diseases[1][2].

Product Specifications

CAS Number

[2839916-15-1]

UNSPSC

12352005

Target

Glycosyltransferase

Related Pathways

Epigenetics

Field of Research

Metabolic Disease

Smiles

O=C([C@H]1N(C[C@@H](C1)F)C(CN2C(C(F)F)=CC=N2)=O)N[C@@H](C3=CC=CC=C3)C4=CC=C(C(C)C)C(F)=N4

Molecular Formula

C26H27F4N5O2

Molecular Weight

517.52

References & Citations

[1]Gulsah Aydin. HIGH-AFFINITY BINDING OF DAPAGLIFLOZIN TO HUMAN GYS1: A STRUCTURE-BASED REPURPOSING STRATEGY FOR LAFORA DISEASE. id health scıence, 2025.|[2]David John Morgans, et al. Inhibitors of glycogen synthase 1 (gys1) and methods of use thereof. WO2022198196A1.