(2R,4R) -UCB7362

(2R,4R) -UCB7362 is the (2R,4R) isomer of UCB7362 (HY-151568) . UCB7362 is an inhibitor of plasma proteinase X (PMX) with antimalarial activity[1].

Product Specifications

CAS Number

[2610631-17-7]

UNSPSC

12352005

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

C[C@@]1(C2=C(C(NC(C3=CC(C#N)=CC=C3)=O)=CC=C2)Cl)CC(N([C@H]4C[C@H](OCC4)C)C(N)=N1)=O

Molecular Formula

C25H26ClN5O3

Molecular Weight

479.96

References & Citations

[1]Lowe MA, et al. Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362. J Med Chem. 2022 Oct 10.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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