Vesatolimod (Standard)
Vesatolimod (Standard) is the analytical standard of Vesatolimod. This product is intended for research and analytical applications. Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC50 of 291 nM.
Product Specifications
CAS Number
1228585-88-3
UNSPSC
12352100
Target
Apoptosis; HBV; HCV; HIV; Reference Standards; Toll-like Receptor (TLR)
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology
Smiles
O=C1NC2=C(N)N=C(OCCCC)N=C2N(CC3=CC=CC(CN4CCCC4)=C3)C1
Molecular Formula
C22H30N6O2
Molecular Weight
410.51
References & Citations
[1]Rebbapragada I, et al. Molecular Determinants of GS-9620-Dependent TLR7 Activation. PLoS One. 2016 Jan 19;11 (1) :e0146835.|[2]Lanford RE, et al. GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees. Gastroenterology. 2013 Feb 13. pii: S0016-5085 (13) 00169-8.|[3]D Tumas, et al. Preclinical Characterization of GS-9620, A Potent and Selective Oral TLR7 Agonist.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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