APD668 (Standard)
APD668 (Standard) is the analytical standard of APD668. This product is intended for research and analytical applications. APD668 is a potent, selective and orally active agonist of G-protein coupled receptor GPR119, with EC50s of 2.7 nM and 33 nM for hGPR119 and rGPR119, respectively. APD668 shows no significant inhibition of any of the five major CYP isoforms with the exception of CYP2C9 (Ki=0.1 μM) . APD668 can be used for the research of steatohepatitis and diabetes[1][2].
Product Specifications
CAS Number
832714-46-2
UNSPSC
12352100
Target
Cytochrome P450; GPR119; Potassium Channel; Reference Standards
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Field of Research
Metabolic Disease
Smiles
O=C(OC(C)C)N(CC1)CCC1OC2=C3C(N(C4=CC=C(S(=O)(C)=O)C=C4F)N=C3)=NC=N2
Molecular Formula
C21H24FN5O5S
Molecular Weight
477.51
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
E-Cadherin / CD324 (Intercellular Junction Marker) (4A2), CF488A conjugate, 0.1mg/mL
Cytokeratin 17 (E3), CF594 conjugate, 0.1mg/mL
Ep-CAM / CD326 (VU-1D9), CF568 conjugate, 0.1mg/mL
